The iMODERN study compared immediate and delayed percutaneous coronary intervention (PCI) of intact lesions in patients with ST-elevation myocardial infarction (STEMI) after successful primary PCI. 1146 patients were included in the study, the average age was 63 years, 78% were men. Patients were randomly divided into two groups: immediate PCI guided by iFR (instantaneous wave-free ratio) and delayed PCI guided by stress magnetic resonance imaging (MRI) within 6 weeks. In the group with immediate PCI, 42.6% of patients underwent the procedure, in the delayed group only 18.7%. At three years, there was no statistically significant difference in the primary endpoint, which included death from any cause, recurrent myocardial infarction, or hospitalization for heart failure (9.3% vs. 9.8%; HR 0.95; p=0.81). The incidence of serious adverse events was similar in both groups. The results confirmed that immediate iFR-guided PCI was not superior to delayed MRI-guided PCI of intact lesions in patients with STEMI at a follow-up of 3 years[1][2][4].