Subcutaneous Dirofilariasis

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Source: NEJM

Original: https://www.nejm.org/doi/full/10.1056/NEJMicm2509643?af=R&rss=currentIssue...

Published: 2025-11-22T12:30:00Z

Subcutaneous dirofilariasis is a rare zoonotic disease caused by a parasite of the genus Dirofilaria, most commonly Dirofilaria repens or Dirofilaria immitis. The case was published in the New England Journal of Medicine, Volume 393, Issue 21, November 27, 2025. The case involves one patient with an atypical location of the finding - in the breast area. Surgical removal yielded a 14.5 cm long worm parasite that was identified as Dirofilaria. The patient was treated with oral antibiotics and diethylcarbamazine, without subsequent recurrence. The main treatment for subcutaneous dirofilariasis is surgical removal of the parasite, or treatment with diethylcarbamazine or ivermectin may also be used. Prevention consists in protection against mosquitoes, especially in endemic areas. The case is exceptional due to its unusual location and occurrence in a non-endemic area.