Spironolactone-Induced Gynecomastia

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Source: NEJM

Original: https://www.nejm.org/doi/full/10.1056/NEJMicm2510742?af=R&rss=currentIssue...

Published: 2025-11-26T10:00:17Z

Spironolactone can cause gynecomastia, which is breast enlargement in men. A case report describes a patient who was given spironolactone and subsequently developed gynecomastia. Spironolactone is a drug used mainly for heart disease and high blood pressure. Gynecomastia is a known side effect of this drug. The article does not provide statistics or exact numbers regarding the incidence of gynecomastia. The case was published as an illustration of the risk associated with the drug spironolactone. The article does not provide an abstract or detailed results of the study. The message serves to warn about a possible side effect of the drug.