Spermine is a small molecule present in the human body that has the potential to help fight Alzheimer's and Parkinson's diseases.This molecule works by neutralizing the harmful accumulations of misfolded proteins associated with these neurodegenerative diseases.Spermine encourages these damaged proteins to assemble into manageable clumps that can be more efficiently removed by cells through autophagy, a natural cell-cleaning process.[1] Studies in model organisms, specifically nematodes, have shown that spermine also increases longevity and promotes cellular energy production.These discoveries create new opportunities for the development of targeted therapies based on polyamines, a group of molecules to which spermine belongs.Scientists are also exploring the use of artificial intelligence to advance the molecular design of new therapeutic approaches.[1