[Articles] Scheduled birth at term for the prevention of pre-eclampsia (PREVENT-PE): an open-label randomised controlled trial

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Source: The Lancet

Original: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01207-3/fullt...

Published: 2025-12-04T23:30:01Z

The PREVENT-PE study is an open randomized controlled trial aimed at preventing preeclampsia by planned delivery at term.[1] Planned preterm delivery based on preeclampsia risk stratification reduced the incidence of preeclampsia.[1] This intervention does not lead to an increase in emergency caesarean section.[1] There was also no higher income for the neonatal care department.[1] The study confirms the effectiveness of this approach in women at high risk of preeclampsia.[1] The main findings show the safety and effectiveness of planned birth without negative effects on the mother or the newborn.[1]