Effects of the computer-assisted rehabilitation environment on patient rehabilitation: a systematic review and meta-analysis

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Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2025.1733273...

Published: 2025-12-05T00:00:00Z

The study investigated the effects of a computer-assisted rehabilitation environment (CAREN) that combines virtual reality, motion sensing systems and real-time feedback. The researchers analyzed 15 studies focusing on patients with neurological and musculoskeletal disorders, of which 9 had enough data for a meta-analysis. CAREN training significantly improved patients' balance, as shown by higher Berg Balance Scale scores (SMD = 1.12), and also improved cognitive function with higher Montreal Cognitive Assessment scores (MD = 0.46). However, the effects on mental health were limited – fear of falling and depressive symptoms did not change significantly. Adverse events were rare and no serious complications were reported. The conclusion of the study suggests that CAREN is particularly effective for improving balance and cognitive abilities, although its impact on psychological health is relatively limited.