Researchers developed a rule to predict bacteremia and bacterial meningitis in febrile infants 28 days of age or younger. The study examined trends in the administration of vitamin K in infants, which is important for the prevention of bleeding disorders in infants. The editorial discusses a shift in the care of febrile newborns so that fewer interventions can be performed. Further research is focused on the development of chimeric T-cell antigen receptor therapy in oncology. Studies are investigating the use of medical cannabis and opioids in adults with chronic pain, as well as the predictive role of circulating tumor DNA in the treatment of colon cancer. Toripalimab-based treatment of nasopharyngeal carcinoma without concomitant cisplatin is discussed.