The study evaluated the optimal volume of programmed intermittent epidural bolus (PIEB) for dural puncture epidural analgesia (DPE) in patients with gestational hypertension during labor. 50 first-time mothers with gestational hypertension aged 22–40 were included in the research. The bolus volume was used in the range of 7 to 12 ml, while the first patient received 7 ml and subsequently the volume was adjusted according to the need for rescue analgesia. This resulted in a PIEB 90% effective volume (EV90) value of 9.8 mL (95% confidence interval 9.52–10.38 mL). Higher bolus volumes were associated with an increased incidence of ≥T6 sensory block, while motor block, fetal bradycardia, and hypotension were also noted at 12 mL, but did not require treatment or were reversible. There were no significant differences in the length of the first and second stages of labor or in the use of antihypertensive drugs. A regimen with EV90 of 9.8 mL PIEB (40-minute interval; ropivacaine 0.08% + sufentanil 0.3 μg/mL) provided effective analgesia with a low risk of adverse effects. The study was registered under the identifier ChiCTR2500099107.