A systematic review analyzed the effectiveness of simulation training for airway management in hospitals during the COVID-19 pandemic based on 20 studies. The results of the meta-analysis showed significant improvements in the confidence and knowledge of health professionals after completing the simulation training, which was confirmed by negative standardized mean differences (SMD, Cohen's d). A sensitivity analysis confirmed the robustness of these results across different correlation estimates. Nevertheless, a high risk of publication bias was identified as funnel plots showed asymmetry and studies were outside the 95% confidence interval. The authors emphasize that simulation training positively affects the preparedness of health care providers for airway management during a pandemic. At the same time, however, they recommend the implementation of other high-quality and unbiased studies to strengthen the evidence base and optimize future training programs for the pandemic. The systematic review was registered under PROSPERO CRD42022293708.