The study retrospectively compared 92 pregnant women divided by trimester (30 in 1st trimester, 34 in 2nd trimester, 28 in 3rd trimester) with 30 non-pregnant controls in the evaluation of standard coagulation tests (PT, APTT, TT, fibrinogen) and thromboelastography parameters (TEG: R, K, α-angle, MA). TEG results showed a gradual decrease in R and K values and an increase in α-angle and MA with the progress of pregnancy between trimesters (p < 0.05), reflecting the onset of a hypercoagulable state. The combination of TEG parameters with standard coagulation tests improved the diagnostic accuracy in the evaluation of coagulation status, with ROC analysis achieving an AUC of 0.876, a sensitivity of 84.0%, and a specificity of 83.6%. The authors report that the observed changes in both TEG and traditional parameters document the physiological adaptation of the coagulation system during pregnancy. The study concludes that integration of TEG with standard tests provides a more comprehensive approach to early detection of coagulation abnormalities and may improve perinatal outcomes, but these findings do not support the routine use of TEG in healthy pregnant women.