The article "Notable advances 2025" published in Nature Medicine on 12 December 2025 summarises the major advances in biomedical research for the year 2025. Despite the many blows the year dealt to biomedical research, it produced inspiring breakthroughs. These advances span fields from regenerative medicine to reproductive technologies and other intermediate disciplines. This is a selection of critical events that have moved medicine forward. The article highlights key events in various fields of medicine[3].