Brief, factual summary in Slovak: The editors of the JAMA magazine selected the research of the year 2025. It was the WISDOM RCT study, which investigated annual breast cancer screening based on risk. The results showed that risk-based screening is more effective than annual screening. The study provided important information about breast cancer prevention. In addition, JAMA Audio Highlights brought discussion of new trends in neonatology and cardiovascular disease risk factors. JAMA magazine also focused on the call for applications for the use of artificial intelligence in medicine.