Platelets are given to patients by transfusion to prevent and stop bleeding. They are normally stored at room temperature of 20–24°C, allowing a shelf life of only 5–7 days due to the risk of bacterial proliferation. Cold storage at 2-6 °C allows to extend the shelf life up to 21 days. Cold-stored platelets are already being used by transfusion in countries such as the United States and Norway. Variations in processing from collection to transfusion, including collection platform, storage solution, and modifications, affect their characteristics during cooling. This variability can alter clinical outcomes after transfusion. The review reevaluates assumptions about chilled wafers and identifies areas for further research and best practices.