A meta-analysis included nine studies with a total of 1954 patients with sepsis and evaluated associations between coagulation markers (APTT, PT, D-dimer, fibrinogen, INR), SOFA score and clinical outcomes[1]. Fibrinogen had a significant inverse association with mortality with OR = 0.76 (95% CI 0.59–0.97)[ 1 ]. INR showed moderate predictive ability with AUC = 0.68[1]. APTT and PT had non-significant odds ratios but moderate diagnostic performances with AUC = 0.75 for both parameters[1]. D-dimer and SOFA scores did not have statistically significant ORs, although the AUC for SOFA indicated good prognostic utility[1]. The work noted high heterogeneity between studies (I2 > 74%) and sensitivity of results to individual studies[1]. The authors state that fibrinogen and INR may be useful in assessing the prognosis of sepsis, but study variability limits generalizability and further high-quality studies are needed[1]. The study is registered in PROSPERO under the identifier CRD420251049209[1].