The establishment of the Lancet Commission on Maternal and Newborn Health is announced.[1][4] Maternal and newborn health is one of the most pressing global health challenges.[1] Every 2 minutes a woman dies from complications of pregnancy or childbirth, every 17 seconds a child dies before birth and 2.3 million newborns die before reaching 1 month of age each year.[1] The commission is led by Mehreen Zaigham from Lund University and Sweden's Skåne University Hospital.[1][2] The group includes researchers, practitioners, policy makers, and people with personal health care experience.[1] The commission examines urgent needs in maternal and newborn health, including the role of new technologies such as digital platforms, telemedicine and AI tools.[1] It plans for change through three pillars: an assessment of past successes and future challenges with recommendations, new research into causes of death and caesarean access, and a road map with a manifesto for the next decade.[1]