The article describes a randomized controlled trial of generative AI-based low-dose digital subtraction angiography to reduce intraoperative radiation dose. The model was trained to generate patient-specific synthetic angiographic images. The study was multicenter and included 1,068 patients. Technology has reduced radiation exposure to patients and doctors by two-thirds. The results were published in Nature Medicine online on January 2, 2026 with doi: 10.1038/s41591-025-04042-6.