An article in Nature Medicine examines blood biomarkers that reveal pathways associated with multimorbidity. Several biological processes contribute to the development of specific combinations of chronic diseases and to the progression of multimorbidity over time. Findings show both shared and specific blood biomarkers for multimorbidity. Metabolic disorders play a central role in multimorbidity. These disorders represent a potential target for interventions to alleviate multimorbidity in older adults. The study suggests that multiple biological processes contribute to multimorbidity through both shared and distinct mechanisms.[1][2][3]