Sleep, Women, and Tau; Prenatal COVID and the Brain; Why FDA Rejected MS Drug

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Source: MedPage Today

Original: https://www.medpagetoday.com/neurology/generalneurology/119300...

Published: Tue, 06 Jan 2026 15:08:41 -0500

Cross-sectional data from a survey of 45 functionally intact elderly women at increased risk of Alzheimer's disease show an association between sleep, APOE4 genotype, and tau protein. Short sleep duration strengthened the association between APOE4 status and tau, while longer sleep moderated the relationship. The study suggests that sleep duration affects risk in women with this genetic risk factor. The article goes on to mention prenatal COVID-19 and its potential impact on brain development, but without specific details. The FDA rejected the multiple sclerosis drug for unspecified reasons listed in the title. These findings come from MedPage Today and highlight the importance of sleep in preventing neurological changes.