The article describes the case of a Neisseria meningitidis strain that changed its serogroup (so-called "serogroup switching") and at the same time carries dual antibiotic resistance. The authors report that the isolated strain showed resistance to two important antibiotics used in the treatment of invasive meningococcal disease. Genetic analysis confirmed that this is the same clonal strain that acquired the new capsular genes responsible for the serogroup change. The article emphasizes that such a combination of serogroup switching and multiple resistance complicates the choice of treatment as well as the evaluation of the effectiveness of vaccines targeting specific serogroups. It is reported to be a rare but clinically significant phenomenon with the potential to impact public health. The authors also point out the need for thorough laboratory monitoring of meningococcal isolates, including serotyping and antibiotic susceptibility testing. The article does not present extensive epidemiological statistics, it focuses on a detailed description of this particular case and its molecular characteristics.