The authors of this correspondence disagree with the statement that there is no evidence for the efficacy of platelet-rich plasma (PRP) in osteoarthritis of the knee. They point out that a conclusion based primarily on the RESTORE trial overlooks important and recent high-quality data on this treatment. PRP is a minimally invasive preparation that is obtained from the patient's own blood and contains platelets rich in growth factors. These growth factors stimulate cell replication and have an angiogenic effect, which supports metabolic and cellular differentiation processes. In orthopedics, PRP is used to regenerate soft tissues such as muscles, tendons, and ligaments, as well as to promote bone tissue healing. The authors claim that there is better and more recent scientific evidence for the effectiveness of PRP in osteoarthritis of the knee than was considered in the aforementioned seminar.