The article discusses the relationship between smokeless tobacco (e.g., chewing tobacco, snuff, betel tobacco) and oral cancer on a global scale.[5]Describes the global burden of smokeless tobacco, its distribution in different regions, and the types of products used.[5]Evidence is summarized that smokeless tobacco contains multiple toxic and carcinogenic substances and that its long-term use increases the risk of oral tumors. cavity. [5] The publication states that the burden is particularly high in South and Southeast Asia, where the use of these products is widespread. [5] The mechanisms of cancer (damage to mucosal cells, the action of carcinogens) as well as the differences in risk according to the type of product and patterns of use are discussed. risk. [5] It also draws attention to the importance of tobacco control policies and intervention programs aimed at limiting the use of smokeless tobacco. [5]