A large prospective study showed that colorectal cancer patients who remained physically active during treatment and recovery had significantly less fatigue. At the same time, they achieved better results in the area of quality of life. The research followed patients with colorectal cancer during their oncological treatment and subsequent recovery period. The analysis confirmed the link between regular physical activity and the alleviation of cancer fatigue. More active patients reported better physical and psychological functioning in everyday life. The study thus points to the importance of maintaining adequate physical activity even during the demanding treatment of colorectal cancer.