[Articles] Profiling vaccine attitudes and subsequent uptake in 1·1 million people in England: a nationwide cohort study

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Source: The Lancet

Original: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01912-9/fullt...

Published: 2026-01-12T23:30:02Z

The study analyzed attitudes to and subsequent vaccination against COVID-19 in 1.1 million people in England in the nationwide REACT cohort study from May 2020 to March 2022.[1][5] A total of 3.3% of participants (37,982 people) reported some degree of vaccine hesitancy.[5] Of these, vaccination data was available through NHS records for 24,229 (64%) persons.[5] Almost two-thirds (65%) of initially hesitant people eventually got vaccinated at least once.[5] The hesitation rate dropped from 8% in January 2021 to 1.1% in early 2022, with a slight increase to 2.2% in February and March 2022 during the Omicron wave.[5] Most of the hesitancy was due to specific concerns that can be addressed and overcome with time and better information availability.[1][5] These findings should help in future vaccination campaigns to promote vaccine uptake.[1]