The study evaluated transbronchial cryobiopsy of the lung using a 1.1 mm cryoprobe in 52 patients with interstitial lung disease. The diagnostic yield was high, 88.5%, which means that a specific diagnosis was established in most cases. A multidisciplinary discussion showed that 50% of cases were interstitial diseases with a known cause, most commonly hypersensitivity pneumonitis. Idiopathic interstitial pneumonias accounted for 19.2%, mostly non-specific interstitial pneumonias, and rare forms of ILD also 19.2%, most often pulmonary alveolar proteinosis. On average, 3.5 tissue samples were obtained per patient and the typical sample diameter was 5 mm. Severe bleeding occurred in 3.8% of cases, extremely severe bleeding was not reported. Pneumothorax occurred in 1.9% of patients and could be managed without chest drainage. The authors conclude that this method provides quality samples and enables accurate classification of interstitial lung disease while maintaining a low risk of complications.