Risk factors for diabetes often appear in multiple members of the same household, an observational study of adults with prediabetes has shown. In the cohort of adults with prediabetes, 75.9% of households with multiple residents had at least one other member with risk factors. Among the household members, risk factors manifested themselves in almost two-thirds of adults (64.6%) and one-third of children (35.0%). A study from Denmark of 7.3 million people identified 343,237 cases of diabetes (4.7%). The relative risk (RR) of diabetes was 2.02 if any relative had diabetes, 1.79 for a father and 2.06 for a mother with diabetes. If both parents had diabetes, the RR reached 3.40, for siblings 2.77 and for twins 5.76. Familial clustering of diabetes is associated with genetic predisposition, with maternal status being the dominant factor, but risk has also been observed in step-relatives and spouses, suggesting an influence of environmental factors.[1][4]