Brief, factual summary of the article in Slovak: The gut-brain axis offers clinical significance for patients with chronic odor syndrome (CSS). Research suggests that the gut-brain axis may play an important role in the pathogenesis and treatment of CSS. Patients with CSS often suffer from gastrointestinal problems, suggesting a connection between the gut and the brain. Further research is needed to better understand this association and its clinical implications for CSS patients. Insights into the gut-brain axis may lead to new therapeutic approaches for CSS patients.