Ibuprofen, a common pain reliever, may reduce the risk of some cancers.[1][4] A 2025 study of more than 42,000 women aged 55 to 74 followed for 12 years showed that women taking at least 30 ibuprofen tablets per month had a 25% lower risk of endometrial cancer compared to those taking less than 4 tablets per month.[1][4] Other studies have linked regular use of ibuprofen to a reduced risk of colon, breast, lung, and prostate cancer.[1][4][6] In smokers, regular use can reduce the risk of lung cancer by up to 48% according to a long-term study of more than 10,000 people.[2] The drug suppresses inflammation that promotes tumor growth and can interfere with genes necessary for cancer cells to survive.[4] Colon cancer patients had a lower risk of recurrence.[3][5] However, experts warn against long-term use due to risks such as stomach ulcers, bleeding or kidney damage, and recommend consulting a doctor.[3]