Integrated analysis of risk factors, visual prognosis, and pathogens in pediatric post-traumatic endophthalmitis: a retrospective cohort study

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Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2026.1699901...

Published: 2026-01-22T00:00:00Z

The study examined pediatric eye trauma with infectious endophthalmitis (inflammation of the inside of the eye) in 108 hospitalized children between January 2019 and June 2025[3]. Among the 108 children, 83 were boys (76.85%) and 98 children (90.74%) came from rural areas[3]. The main risk factors for the development of infectious endophthalmitis were delayed medical consultation and increased values โ€‹โ€‹of inflammatory markers, especially the number of white blood cells (WBC), which was identified as an independent risk factor with a diagnostic accuracy of AUC 0.722[3]. Poor visual prognosis was associated with endophthalmitis, lens injury and elevated inflammatory markers, with a combined diagnostic accuracy of AUC 0.732[3]. Among culture-positive cases, bacterial infection dominated (81.48%), especially gram-positive cocci such as Staphylococcus and Streptococcus, which were sensitive to cephalosporin, penicillin, vancomycin and fluoroquinolones[3]. Patients with less severe lens damage and lower levels of inflammatory markers were more likely to achieve favorable visual outcomes[3].