The study examined the antimicrobial resistance of bacteria in Goma, Democratic Republic of the Congo, between September 2019 and March 2022. The researchers tested 341 bacterial isolates from clinical samples and found that Escherichia coli was the most common (about 27%), followed by Klebsiella pneumoniae and Enterococcus faecalis. In E. coli bacteria, resistance to the commonly used drugs ampicillin, amoxicillin/clavulanate and ciprofloxacin exceeded 60%. Klebsiella pneumoniae showed complete resistance to ampicillin and high resistance to other drugs including cefuroxime, cefotaxime, gentamicin and colistin. The authors conclude that antimicrobial resistance is a major public health problem in Goma and that current empiric treatment regimens are becoming less effective. They recommend strengthening laboratory capacity, establishing continuous surveillance, and participating in international WHO resistance monitoring programs.