Catheter-related bloodstream infections (CRBSIs) are a major clinical complication with a 28-day mortality rate of 19.77% in this study of 172 patients.[6] The incidence of CRBSIs decreased significantly between 2021 and 2024, with nephrology (34.88%), intensive care unit (22.21%), and gastroenterology (12.21%) occurring most frequently.[6] Gram-positive microorganisms accounted for the majority of cases (51.74%), with Staphylococcus aureus being the main pathogen (41.28%), while Escherichia coli and Klebsiella pneumoniae showed increasing trends.[6] High APACHE II scores and cardiovascular disease were independent predictors of higher mortality, while carbapenem-resistant infections (Acinetobacter baumannii and Klebsiella pneumoniae) were associated with higher mortality.[6] Conversely, infections with gram-positive microorganisms were associated with more favorable outcomes.[6] Strengthening infection control has effectively reduced the incidence of CRBSI, highlighting the need for increased surveillance in high-risk wards and continuous monitoring of antimicrobial resistance.[6]