Heavy alcohol drinking is associated with a higher risk of colorectal cancer, particularly rectal cancer, according to data from the PLCO prospective screening.[1] Alcohol intake greater than 30 grams of ethyl alcohol per day is considered a risky dose and is associated with a slightly relative increase in the risk of developing colorectal cancer.[1] Alcoholic beverages are classified as group 1 carcinogens, which means they are proven human carcinogens.[2] The risk is higher in beer and hard alcohol consumers compared to wine consumers.[4] The mechanism of damage is that alcohol consumption leads to the formation of the toxic substance acetaldehyde, which damages DNA and can cause cellular changes leading to cancer.[3] According to epidemiological studies, there is strong evidence of a causal relationship between alcohol consumption and colon cancer in men and a probable causal relationship in women.[2] Alcohol is one of the main modifiable risk factors for colorectal cancer, which can be avoided with the right lifestyle.