The Lang Youth Medical Program (LYMP) is a 6-year hospital-based program for high school students in Northern Manhattan that immerses them in the health sciences and clinical curriculum. The program includes a body systems-based curriculum, clinical skills lessons, hospital tours, summer internships, and support with high school and college applications. Families receive parenting workshops and links to counseling services. With a 92.6% retention rate across 16 graduating cohorts, approximately 93% of graduates go on to college and one in five have a college degree. Among graduates with a university degree, 26% (n=30) returned full-time to the host hospital. Graduates score 27% higher on standardized tests than their peers and report being well-prepared with professional and academic skills. The program offers a replicable model for improving educational outcomes and health literacy among underrepresented youth.