STAT+: New startup to develop a GLP-1 drug for addiction

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Source: STAT News

Original: https://www.statnews.com/2026/01/27/biotech-news-glp-1-drug-for-addiction-startu...

Published: Tue, 27 Jan 2026 14:40:31 +0000

The new startup STAT+ is focused on the development of a GLP-1-based drug for the treatment of addiction.[1] GLP-1 drugs, such as Ozempic or Wego, suppress hunger, promote weight loss, and regulate blood sugar levels by affecting hormones in the body.[2][5][6] After stopping these drugs, patients often experience a return of intense hunger, weight gain, and the yo-yo effect.[1][2][3] An example is patient Tanya Hall, who lost 38 kg on Wegos, but gained weight after stopping due to an uncontrollable appetite.[1] Studies show that treatment with semaglutide at a dose of 2.4 mg for 68 weeks resulted in a 17.4% weight loss compared to placebo and a 35% reduction in food intake.[6] Medication may be needed for life to prevent relapse.[1][2] Side effects include muscle loss, digestive problems, decreased saliva production, and the risk of counterfeit versions sold illegally.[1][4][7] ŠÚKL warns of a sharp increase in the supply of falsified GLP-1 drugs, which may contain dangerous substances and require a prescription and medical supervision.[4]