Researchers compared the cost-effectiveness of four fibromyalgia drugs: amitriptyline, duloxetine (Cymbalta), and pregabalin. One of these drugs achieved the best value according to a comparative study. The study analyzed data on drug costs and clinical effectiveness. Published data show that the selected drug came out on top in this evaluation. The study included four drugs approved for the treatment of fibromyalgia. The main finding is that this drug offers the best price-performance ratio.