A review has shown that gut dysbiosis is a common feature of mild cognitive impairment and Alzheimer's disease.[1] In people with Alzheimer's disease, an increased occurrence of Pseudomonads and Actinomycetos bacteria has been reported in several studies.[1] Gut dysbiosis leads to systemic inflammation, neuroinflammation and amyloid β deposition.[1][2] In patients with cognitive disorders, the number of anti-inflammatory bacteria such as Eubacterium rectale and Bacteroides fragilis is reduced, on the contrary, the number of pro-inflammatory Escherichia and Shigella is increased.[1] A 2017 Swedish study demonstrated that dysbiotic gut flora in mice with Alzheimer's disease accelerates disease progression and promotes the formation of brain plaques.[2] Colonization of germ-free mice with Alzheimer's disease bacteria led to plaque formation, while bacteria from healthy individuals significantly reduced them.[2] Gut dysbiosis disrupts the intestinal barrier, causes metabolic endotoxemia, and contributes to brain amyloidosis.[1]