A case report of acute hyperlipidemic pancreatitis after blastocyst transfer and literature review

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Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2026.1698359...

Published: 2026-02-04T00:00:00Z

A 38-year-old woman with type 1 diabetes and nonalcoholic fatty liver disease presented with abdominal pain, nausea, and vomiting nine days after blastocyst transfer during assisted reproduction.[1] She was diagnosed with hyperlipidemic pancreatitis, which typically occurs when triglycerides rise above 1,000 mg/dL.[1] High levels of triglycerides cause increased blood viscosity and impaired blood flow, leading to pancreatic capillary occlusion and local ischemia.[1] The patient was treated with fasting, plasmapheresis, and insulin, while also receiving fenofibrate, ulinastatin, latamoxef, and traditional Chinese medicine.[1] Plasmapheresis rapidly reduced the concentration of triglycerides and chylomicrons in the circulation and stopped further inflammatory processes and damage to the pancreas.[1] After two days, the relevant parameters of the patient significantly decreased, the symptoms improved, and she was transferred to the general ward for continued treatment.[1]