WHO announces the resumption of global cholera vaccination programs after a nearly 4-year hiatus caused by vaccine shortages. The announcement was made on Wednesday by the World Health Organization (WHO) together with the vaccination alliance GAVI and UNICEF. These promotions are restarting after a long period of restrictions. In 2025, a total of 614,828 cholera cases and 7,598 deaths were reported from 33 countries across five WHO regions.[1] The Eastern Mediterranean region recorded the most cases, followed by the African region, the Southeast Asian region, the Americas region, and the Western Pacific region.[1] In December 2025, there were 17,327 new cases of cholera and acute watery diarrhea from 16 countries in three regions, a 25% decrease from November, along with 137 deaths, a 16% decrease.[1] In the first weeks of 2026, there was a significant decrease in reported cases of cholera compared to the same period last year.[2]