The article discusses director Chloé Zhao's film adaptation of Maggie O'Farrell's book Hamnet, released in 2020 at the start of the COVID-19 pandemic. It describes a time of social isolation, images of ventilators and families saying goodbye over the phone, as well as memories of health workers of screams and silence in hospitals. After nearly six years, he wonders where the great novel about COVID-19 is. Literature has historically responded to contagion and walked with human horror and fear. The audience is sensitive to the story of the consequences of the pandemic in Hamnet, where the Black Death is involved. The film depicts the family of William Shakespeare and Agnes following the death of their 11-year-old son Hamnet.[3][5]