A panorama of plant pangenomes

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Source: Science Magazine

Original: https://www.science.org/doi/abs/10.1126/science.aee6527?af=R...

Published: 2026-02-05T07:00:12Z

The article provides an overview of the evolution of plant pangenomes that capture genetic variability across species, subspecies and genera. Pangenomics focuses mainly on crops with high diversification and polyploidy. Ma et al. constructed a pangenome for Brassica rapa from 1720 examples of seven subspecies, revealing structural variants and regions associated with phenotypes. Huang et al. developed a multiscale graph pangenome for the polyploid sugarcane Saccharum from nine assemblies of four species, where each homologous chromosome set contains 47 to 57 haplotypes and 74,000 to 271,000 gene alleles. These pangenomes help identify presence-absence variants of genes such as 503 PAVs relevant to beet diversification. They serve as a resource for crop improvement and the study of domestication. The authors compare this progress with the discoveries of protein variability 60 years ago in Drosophila and humans.[1][2][3]