A study investigated the incidence of ANCA-associated vasculitis (a rare autoimmune disease) before and during the COVID-19 pandemic in a Spanish hospital from January 2019 to December 2022[7]. The results showed a temporary increase in the number of new diagnoses during the pandemic, with approximately 40% of patients diagnosed during this period having a recent SARS-CoV-2 infection or having been vaccinated against COVID-19 in the previous three months[7]. By 2022, the incidence of the disease has returned to the pre-pandemic level[7]. Demographic and clinical characteristics of patients, such as age, sex, disease severity, and affected organs, remained stable between the pre-pandemic and pandemic periods[7]. During the pandemic, there was a numerical increase in cases with PR3-ANCA, while MPO-ANCA remained the predominant subtype[7]. The authors state that these findings suggest a possible temporal association between infection or vaccination with COVID-19 and the development of vasculitis and emphasize the need for further larger studies to confirm these observations[7].