Natural dyes are obtained from natural materials such as plants, animals and mineral resources, for example by extraction from vegetables, fruits, seeds or roots.[1] They are among the three main types of dyes, along with nature-identical and synthetic, with synthetic and nature-identical being chemically produced.[1] An example is carmine, which has a relatively high stability compared to other natural dyes and is found in preparations such as Aqua carminativa rubra or Q max active 30 tbl.[1] Its ADI value was set by JECFA at 0–5 mg/kg body weight after a review in 2000.[1] Chlorophyll exists in two variants, A and B, differing by a substitutional change on the B ring, occurring in a 3:1 ratio in plants, where variant A is less stable and has a bluer green.[1] As a natural dye, indigo comes from the Indigofera tinctoria plant and its extraction involves fermentation, centrifugation, straining, pressing and drying into cakes.[5] Natural dyes must have properties such as intense coloring, affinity to fibers in a concentration of 0.5 to 3% of the weight of the material, and harmless to health.[2] They are divided according to their structure into polyene, quinone and other types.[2]