Correction: Identification of two novel MVD mutations and one novel FDPS mutation in Chinese patients with porokeratosis

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Source: Frontiers Medicine

Original: https://www.frontiersin.org/articles/10.3389/fmed.2026.1799246...

Published: 2026-02-09T00:00:00Z

The article is a correction of a study on the identification of two new mutations in the MVD gene and one new mutation in the FDPS gene in Chinese patients with porokeratosis.[1][5] Porokeratosis is an inherited disease characterized by abnormal keratinization of the skin, caused by mutations in mevalonate pathway genes such as MVD, MVK, PMVK, and FDPS.[5] In the authors' previous research, a novel MVD mutation (c.683G>C), a novel FDPS mutation (c.438T>G), and three previously known MVD mutations (c.11111113del, c.875A>G, c.746T>C) were discovered in cases from Jiangxi Province, China.[5] The study analyzed mutations in these genes in seven sporadic cases of porokeratosis.[5] These findings contribute to the understanding of the spectrum of mutations associated with porokeratosis.[5]