The author of the article wrote about the over-prescription of antidepressants more than ten years ago. Today, 17% of the population is prescribed antidepressants. At best, seven people must be treated for one of them to benefit. For most patients, antidepressants offer no meaningful advantage over placebo. In moderate depression, antidepressants may not work at all. Clinical depression is an arbitrarily defined set of symptoms and timelines. Depression is a psychological adaptive response and a tool for behavior change. There is no conclusive evidence that antidepressants reduce suicide, and higher prescribing rates are associated with poorer overall well-being.