The article describes the case of a 39-year-old man who suffered a severe brain injury after falling from a height and was also affected by polytrauma. In his treatment, doctors applied the innovative eight-dimensional GHOST-CAP strategy in combination with real-time multimodal neurological monitoring. This strategy made it possible to dynamically adjust therapeutic goals during treatment based on continuous monitoring of the patient's condition. During the complex treatment, the patient's health gradually improved. The case demonstrates that the combination of the GHOST-CAP strategy with multimodal monitoring is clinically feasible and can be effective in the treatment of patients with polytrauma complicated by ultra-severe brain injury.