Sorry, but I do not have access to the full text of this article from the New England Journal of Medicine. In order to create an accurate and factual summary in accordance with your requirements, I would need to have access to the entire content of the article. I can help you in the following ways: - If you provide me with the text of the article or a larger part of it, I will create a brief summary according to your specifications - If you have access to the article through your institution, you can send me the relevant passages Without direct access to the article, I would not be able to comply with your request for verified facts and concrete data from the text.