The Oregon Health and Science University (OHSU) Board of Regents has unanimously approved the initiation of negotiations with the US National Institutes of Health (NIH) about the possible transformation of the Oregon National Primate Research Center (ONPRC) into a non-research primate sanctuary.[1][2][5] The NIH proposed exploring federal support for this transformation, which would cost $220 to $291 million over 8 years.[1][2] The center, on a 67-acre campus in Beaverton, currently hosts more than 5,000 monkeys, only two-thirds of which have access to large outdoor enclosures.[1][3] The transition involves a six-month negotiation period during which most monkey breeding will be suspended, but researchers can apply for new grants.[3][5] The center has more than $7.5 million in federally funded neuroscience projects underway and a $13.7 million NIH infrastructure grant through April 30.[2] OHSU plans to seek investment in new methods such as biofabrication and gene therapy, in line with the NIH's initiative to reduce the use of animals in research.[4][5]