Colorectal cancer, a cancer of the colon and rectum, is on the rise in younger adults aged 20 to 49, with 2 to 4% of new cases occurring each year[1][3][9]. The most significant increase is among people under 35 years of age[1][3]. In Slovakia, it is responsible for approximately 15% of all cancer deaths and an average of 32 Slovaks die from it per week[1][2]. More than 4,500 cases are detected annually in both men and women[4]. Between 1995 and 2019, the incidence in people under 55 doubled, and the number of deaths in people under 50 has almost doubled since 1995[2][3][5]. People born after 1990 have twice the risk of colon cancer and four times the risk of rectal cancer than those born in 1950[2][4]. Most of the diagnosed young patients are in an advanced stage[2]. In the US, the screening recommendation has moved from age 50 to age 45[1][6].