Higher levels of physical activity after a cancer diagnosis have a significant effect on reducing the risk of cancer mortality, as evidenced by data from six large cohort studies. Research shows that regular exercise changes the composition of the blood and can slow the growth of cancer cells – just 10 minutes of vigorous exercise causes extensive genetic changes in cancer cells, changing the activity of more than 1,300 genes. After one workout, the levels of myokines such as decorin, interleukin-6 and SPARC increase by 9 to 47 percent, while the growth of cancer cells is reduced. Exercise reduces the risk of premature death by up to 40 percent, the risk of heart disease by 40 percent, and the risk of cancer by 25 percent. 150 minutes of moderate movement a week or even just two days a week with intense exercise is enough. Exercise is considered a therapeutic intervention in cancer management with proven safety and efficacy both during and after treatment. However, the positive effects are lost if people stop being active and their risk returns to the level of inactive people.