The study investigated the effectiveness of platelet-rich fibrin (PRF) in preserving the alveolar ridge after tooth extraction. The analysis included eighteen randomized controlled trials that compared the PRF group with the spontaneous healing group. The PRF group showed significantly less loss in alveolar bone height at 3 months, 4 months, and 6 months compared to the non-PRF group. The use of PRF also resulted in a significantly lower reduction in alveolar bone width at 2 and 3 months. The percentage of new bone formation was significantly higher in the PRF group than in the spontaneous healing group at both 3 and 4 months. High-speed centrifugation was associated with significantly greater new bone formation than standard protocols. The study concluded that PRF attenuates alveolar bone resorption and can increase new bone formation during healing, thus representing a promising option for preserving alveolar bone as a safe autologous biomaterial.