Advances in bioengineering, particularly CRISPR technology, make it possible to precisely edit DNA and correct genetic defects such as thalassemia. Synthetic biology and artificial intelligence contribute to faster research and development of new biological technologies. The same tools and knowledge that are used to develop medical therapies can potentially be misused to create biological threats. For example, advanced machine learning models can design genetically engineered nanobots targeted to specific organs or systems in the human body that can fight cancer when used correctly but cause organ failure or death when used incorrectly. Current detection systems are not efficient enough to distinguish between these different uses of the same technology and identify potential biological threats.